Manuscripts

  1. Ma D, Feitosa MF, Wilk JB, Laramie JM, Yu K, Leiendecker-Foster C, Myers RH, Province MA, Borecki IB.  Leptin is Associated with Blood Pressure and Hypertension in Women From the National Heart, Lung, and Blood Institute Family Heart Study.  Hypertension. 2009;53:473-479.
  2. Latourelle JC, Sun M, Lew MF, Suchowersky O, Klein C, Golbe LI, Mark MH, Growdon JH, Wooten GF, Watts RL, Guttman M, Racette BA, Perlmutter JS, Ahmed A, Shill HA, Singer C, Goldwurm S, Pezzoli G, Zini M, Saint-Hilaire MH, Hendricks AE, Williamson S, Nagle MW, Wilk JB, Massood T, Huskey KW, Laramie JM, Destefano AL, Baker KB, Itin I, Litvan I, Nicholson G, Corbett A, Nance M, Drasby E, Isaacson S, Burn DJ, Chinnery PF, Pramstaller PP, Al-Hinti J, Moller AT, Ostergaard K, Sherman SJ, Roxburgh R, Snow B, Slevin JT, Cambi F, Gusella JF, Myers RH.  The Gly2019Ser mutation in LRRK2 is not fully penetrant in familial Parkinson’s Disease: the GenePD study.  BMC Med. 2008 Nov 5;6(1):32.
  3. Tobin JE, Latourelle JC, Lew MF, Klein C, Suchowersky O, Shill HA, Golbe LI, Mark MH, Growdon JH, Wooten GF, Racette BA, Perlmutter JS, Watts R, Guttman M, Baker KB, Goldwurm S, Pezzoli G, Singer C, Saint-Hilaire MH, Hendricks AE, Williamson S, Nagle MW, Wilk JB, Massood T, Laramie JM, DeStefano AL, Litvan I, Nicholson G, Corbett A, Isaacson S, Burn DJ, Chinnery PF, Pramstaller PP, Sherman S, Al-hinti J, Drasby E, Nance M, Moller AT, Ostergaard K, Roxburgh R, Snow B, Slevin JT, Cambi F, Gusella JF, Myers RH.  Haplotypes and gene expression implicate the MAPT region for Parkinson disease: The GenePD Study.  Neurology. 71:29-35, 2008.
  4. DeStefano AL, Latourelle J, Lew MF, Suchowersky O, Klein C, Golbe LI, Mark MH, Growdon JH, Wooten GF, Watts R, Guttman M, Racette BA, Perlmutter JS, Marlor L, Shill HA, Singer C, Goldwurm S, Pezzoli G, Saint-Hilaire MH, Hendricks AE, Gower A, Williamson S, Nagle MW, Wilk JB, Massood T, Huskey KW, Baker KB, Itin I, Litvan I, Nicholson G, Corbett A, Nance M, Drasby E, Isaacson S, Burn DJ, Chinnery PF, Pramstaller PP, Al-Hinti J, Moller AT, Ostergaard K, Sherman SJ, Roxburgh R, Snow B, Slevin JT, Cambi F, Gusella JF, Myers RH. Replication of association between ELAVL4 and Parkinson disease: the GenePD study.  Hum Genet. 2008 Aug;124(1):95-9.
  5. Walter RE, Wilk JB, Larson MG, Vasan RS, Keaney JF, Lipinska I, O’Connor GT, Benjamin EJ. Systemic inflammation and COPD: The Framingham Heart Study. Chest 2008, 133:19-25.
  6. Wilk JB, Laramie JM, Latourelle JC, Williamson S, Nagle MW, Tobin JE, Leiendecker Foster C, Eckfeldt JH, Province MA, Borecki IB, Myers RH. NYD-SP18 is associated with obesity in the NHLBI Family Heart Study. Int J Obes. 32:930-5, 2008.
  7. Laramie JM, Wilk JB, Williamson SL, Nagle MW, Latourelle JC, Tobin JE, Province MA, Borecki IB, Myers RH. Polymorphisms near EXOC4 and LRGUK on chromosome 7q32 are associated with Type 2 Diabetes and fasting glucose; The NHLBI Family Heart Study. BMC Med Genet 2008, 9:46.
  1. Wilk JB, Walter RE, Laramie JM, Gottlieb DJ, O’Connor GT. Framingham Heart Study genome-wide association: results for pulmonary function measures. BMC Med Genet 2007, 8(Suppl 1):S8.
  2. Gottlieb DJ, O’Connor GT, Wilk JB. Genome-wide association of sleep and circadian phenotypes. BMC Med Genet 2007, 8(Suppl 1):S9.
  3. Cupples LA, Arruda HT, Benjamin EJ, D’Agostino RB Sr, Demissie S, Destefano AL, Dupuis J, Falls KM, Fox CS, Gottlieb DJ, Govindaraju DR, Guo CY, Heard-Costa NL, Hwang SJ, Kathiresan S, Kiel DP, Laramie JM, Larson MG, Levy D, Liu CY, Lunetta KL, Mailman MD, Manning AK, Meigs JB, Murabito JM, Newton-Cheh C, O’connor GT, O’donnell CJ, Pandey M, Seshadri S, Vasan RS, Wang ZY, Wilk JB, Wolf PA, Yang Q, Atwood LD. The Framingham Heart Study 100K SNP genome-wide association study resource: overview of 17 phenotype working group reports. BMC Med Genet. 2007, 8(Suppl 1):S1.
  4. Laramie JM, Wilk JB, DeStefano AL, Myers RH (2007): HaploBuild: an algorithm to construct non-contiguous associated haplotypes in family based genetic studies. Bioinformatics. 23:2190-92.
  5. Wilk JB, Lash TL (2007): Risk factor studies of age-at-onset in a sample ascertained for Parkinson disease affected sibling pairs: a cautionary tale. Emerg Themes Epidemiol 4:1.
  6. Tobin JE, Cui J, Wilk JB, Latourelle JC, Laramie JM, McKee AC, Guttman M, Karamohamed S, Destefano AL, Myers RH (2007): Sepiapterin reductase expression is increased in Parkinson’s disease brain tissue. Brain Res 1139:42-7.
  7. Wilk JB, Herbert A, Shoemaker CM, Gottlieb DJ, Karamohamed S (2007): Secreted Modular Calcium-Binding Protein 2 Haplotypes are Associated with Pulmonary Function. Am J Respir Crit Care Med 175:554-60.
  8. Wilk JB, Tobin JE, Suchowersky O, Shill H, Klein C, Wooten GF, Lew M, Mark MH, Guttman M, Watts RL, Singer C, Growdon J, Latourelle JC, Saint-Hilaire M, DeStefano AL, Prakash R, Williamson S, Berg CJ, Sun M, Goldwurm S, Pezzoli G, Racette BA, Perlmutter JS, Parsian A, Baker K, Giroux ML, Litvan I, Pramstaller PP, Nicholson GA, Burn DJ, Chinnery PF, Vieregge P, Slevin JT, Cambi F, MacDonald ME, Gusella JF, Myers RH, Golbe LI (2006): Herbicide exposure modifies GSTP1 haplotype association to Parkinson onset age: The GenePD Study. Neurology 67:2206-10.
  9. North KE, Carr JJ, Borecki IB, Kraja A, Province MA, Pankow JS, Wilk JB, Hixson JE, Heiss G; for the FHS Investigators (2007): QTL-specific genotype-by-smoking interaction and burden of calcified coronary atherosclerosis: The NHLBI Family Heart Study. Atherosclerosis 193:11-19.
  10. Wilk JB. (2006) Reporting Association to Hypertension: Rare Genotypes with Protective Effects or Common Genotypes Increasing Risk. Am J Hypertens. 19:1166.
  11. Wilk JB, Myers RH, Pankow JS, Hunt SC, Leppert MF, Freedman BI, Province MA, Ellison RC. (2006) Adrenergic receptor polymorphisms associated with resting heart rate: The HyperGEN Study. Ann Hum Genet 70:566-73.
  12. Sun M, Latourelle JC, Wooten GF, Lew MF, Klein C, Shill HA, Golbe LI, Mark MH, Racette BA, Perlmutter JS, Parsian A, Guttman M, Nicholson G, Xu G, Wilk JB, Saint-Hilaire MH, DeStefano AL, Prakash R, Williamson S, Suchowersky O, Labelle N, Growdon JH, Singer C, Watts RL, Goldwurm S, Pezzoli G, Baker KB, Pramstaller PP, Burn DJ, Chinnery PF, Sherman S, Vieregge P, Litvan I, Gillis T, MacDonald ME, Myers RH, Gusella JF. (2006) Influence of heterozygosity for parkin mutation on onset age in familial Parkinson disease: the GenePD study. Arch Neurol. 63:826-32.
  13. Tang W, Arnett DK, Province MA, Lewis CE, North K, Carr JJ, Pankow JS, Hopkins PN, Devereux RB, Wilk JB, Wagenknecht L. (2006) Racial differences in the association of coronary calcified plaque with left ventricular hypertrophy: the national heart, lung, and blood institute family heart study and hypertension genetic epidemiology network. Am J Cardiol. 97:1441-8.
  14. Laramie JM, Wilk JB, Hunt SC, Ellison RC, Chakravarti A, Boerwinkle E, Myers RH (2006): Evidence for a Gene Influencing Heart Rate on Chromosome 5p13-14 in a Meta-Analysis of Genome-Wide Scans from the NHLBI Family Blood Pressure Program. BMC Med Genet 7:17.
  15. Bradbury BD, Wilk JB, Aschengrau A, Lash TL (2006): Departure from multiplicative interaction for catechol-O-methyltransferase genotype and active/passive exposure to tobacco smoke among women with breast cancer. J Carcinog 5:3+.
  16. Karamohamed S, Latourelle JC, Racette BA, Perlmutter JS, Wooten GF, Lew MF, Klein C, Shill H, Golbe LI, Mark MH, Guttman M, Nicholson G, Wilk JB, Saint-Hilaire MH, DeStefano AL, Prakash R, Williamson S, Tobin J, Suchowersky O, Labelle N, Growdon JH, Singer C, Watts RL, Goldwurm S, Pezzoli G, Baker KB, Giroux ML, Pramstaller PP, Burn DJ, Chinnery PF, Sherman S, Vieregge P, Litvan I, Gusella JF, Myers RH, Parsian A (2005): BDNF genetic variants are associated with onset age of familial Parkinson disease: GenePD study. Neurology 65:1823-1825.
  17. Rasmussen-Torvik LJ, North KE, Gu CC, Lewis CE, Wilk JB, Chakravarti A, Chang YC, Miller MB, Li N, Devereux RB, Arnett DK (2005): A Population Association Study of Angiotensinogen Polymorphisms and Haplotypes With Left Ventricular Phenotypes. Hypertension 46:1294-1299.
  18. Bradbury BD, Wilk JB, Kaye JA (2005): Obesity and the risk of prostate cancer. Cancer Causes Control 16:637-641.
  19. Karamohamed S, Golbe LI, Mark MH, Lazzarini AM, Suchowersky O, Labelle N, Guttman M, Currie LJ, Wooten GF, Stacy M, Saint-Hilaire M, Feldman RG, Liu J, Shoemaker CM, Wilk JB, DeStefano AL, Latourelle JC, Xu G, Watts R, Growdon J, Lew M, Waters C, Vieregge P, Pramstaller PP, Klein C, Racette BA, Perlmutter JS, Parsian A, Singer C, Montgomery E, Baker K, Gusella JF, Herbert A, Myers RH (2005): Absence of previously reported variants in the SCNA (G88C and G209A), NR4A2 (T291D and T245G) and the DJ-1 (T497C) genes in familial Parkinson’s disease from the GenePD study. Mov Disord 20: 1188-1191.
  20. Lash TL, Bradbury BD, Wilk JB, Aschengrau A (2005): A case-only analysis of the interaction between N-acetyltransferase 2 haplotypes and tobacco smoke in breast cancer etiology. Breast Cancer Research 7:R385-R393.
  21. Wilk JB, Djousse L, Arnett DK, Hunt SC, Province MA, Heiss G, Myers RH (2004): Genome-wide linkage analyses for age at diagnosis of hypertension and early-onset hypertension in the HyperGEN Study. Am J Hypertens 17:839-844.
  22. Jiang Y, Wilk JB, Borecki I, Williamson S, DeStefano AL, Xu G, Liu J, Ellison RC, Province M, Myers RH (2004): Common variants in the 5’ region of the Leptin gene are associated with Body Mass Index in Men from the NHLBI Family Heart Study. Am J Hum Genet 75:220-230.
  23. Wilk JB, DeStefano AL, Joost O, Myers RH, Cupples LA, Slater K, Atwood LD, Heard-Costa NL, Herbert A, O’Connor GT, Gottlieb DJ (2003): Linkage and Association with Pulmonary Function Measures on Chromosome 6q27 in the Framingham Heart Study. Hum Mol Genet 12:2745-2751.
  24. Karamohamed S, DeStefano AL, Wilk JB, Shoemaker CM, Golbe LI, Mark MH, Lazzarini AM, Suchowersky O, Labelle N, Guttman M, Currie LJ, Wooten GF, Stacy M, Saint-Hilaire M, Feldman RG, Sullivan KM, Xu G, Watts R, Growdon J, Lew M, Waters C, Vieregge P, Pramstaller PP, Klein C, Racette BA, Perlmutter JS, Parsian A, Singer C, Montgomery E, Baker K, Gusella JF, Fink SJ, Myers RH, Herbert A (2003): A haplotype at the PARK3 locus influences onset age for Parkinson disease: The GenePD study. Neurology 61:1557-1561.
  25. Knox SS, Wilk JB, Zhang Y, Weidner G, Ellison RC (2004) A Genome Scan for Hostility: The National Heart, Lung, and Blood Institute Family Heart Study. Mol Psychiatry 9:124-126.
  26. Wilk JB, DeStefano AL, Arnett DK, Rich SS, Djousse L, Crapo RO, Leppert MF, Province MA, Cupples LA, Gottlieb DJ, Myers RH (2003): A Genome-Wide Scan of Pulmonary Function Measures in the National Heart, Lung, and Blood Institute Family Heart Study. Am J Respir Crit Care Med 167:1528-1533.
  27. Wilk JB, Myers RH, Zhang Y, Lewis CE, Atwood LD, Hopkins PN, Ellison RC (2002): Evidence for a gene influencing heart rate on chromosome 4 among hypertensives. Hum Genet 111:207-213.
  28. DeStefano AL, Lew MF, Golbe LI, Mark MH, Lazzarini AM, Guttman M, Montgomery E, Waters CH, Singer C, Watts RL, Currie LJ, Wooten GF, Maher NE, Wilk JB, Sullivan KM, Slater KM, Saint-Hilaire MH, Feldman RG, Suchowersky O, Lafontaine AL, Labelle N, Growdon JH, Vieregge P, Pramstaller PP, Klein C, Hubble JP, Reider CR, Stacy M, MacDonald ME, Gusella JF, Myers RH (2002): PARK3 influences age at onset in Parkinson disease: A genome scan in the GenePD Study. Am J Hum Genet 70:1089-1095.
  29. Maher NE, Currie LJ, Lazzarini AM, Wilk JB, Taylor CA, Saint-Hilaire MH, Feldman RG, Golbe LI, Wooten GF, Myers RH (2002): Segregation Analysis of Parkinson Disease Revealing Evidence For A Major Causative Gene. Am J Med Genet 109:191-197.
  30. Joost O, Wilk JB, Cupples LA, Harmon M, Shearman AM, Baldwin CW, O’Connor GT, Myers RH, Gottlieb DJ (2002): Genetic Loci Influencing Lung Function: A Genome-wide Scan in the Framingham Study. Am J Respir Crit Care Med 165:795-799.
  31. Maher NE, Golbe LI, Lazzarini AM, Mark MH, Currie LJ, Wooten GF, Saint-Hilaire M, Wilk JB, Volcjak J, Maher JE, Feldman RG, Guttman M, Lew M, Schuman S, Suchowersky O, Lafontaine AL, Labelle N, Vieregge P, Pramstaller PP, Klein C, Hubble J, Reider C, Growdon J, Watts R, Montgomery E, Baker K, Singer C, Stacy M, Myers RH (2002): Epidemiologic Study of 203 Sibling Pairs with Parkinson’s Disease: The GenePD Study. Neurology 58:79-84.
  32. Gottlieb DJ, Wilk JB, Harmon M, Evans JC, Joost O, Levy D, O’Connor GT, Myers RH (2001): Heritability of Longitudinal Change in Lung Function: The Framingham Study. Am J Respir Crit Care Med 164:1655-1659.
  33. Heard-Costa NL, Demissie S, DeStefano AL, Knowlton BA, Maher NE, Myers RH, Volcjak JS, Wilk JB, Cupples LA (2001): Influence of Marker Heterozygosity and Genetic Heterogeneity on Fine Mapping. Genet Epidemiol 21 (Suppl 1): S467-S472.
  34. Wilk JB, Volcjak JS, Myers RH, Maher NE, Knowlton BA, Heard-Costa NL, Demissie S, Cupples LA, DeStefano AL (2001): Family-Based Association Tests for Qualitative and Quantitative Traits using Single-Nucleotide Polymorphism and Microsatellite Data. Genet Epidemiol 21(Suppl 1): S364-S369.
  35. Wilk JB, Djousse L, Borecki I, Atwood LD, Hunt SC, Rich SS, Eckfeldt JH, Arnett DK, Rao DC, Myers RH (2000): Segregation Analysis of Serum Uric Acid in the NHLBI Family Heart Study. Hum Genet 106:355-359.
  36. Wilk JB, Djousse L, Arnett DK, Rich SS, Province MA, Hunt SC, Crapo RO, Higgins M, Myers RH (2000): Evidence for Major Genes Influencing Pulmonary Function in the NHLBI Family Heart Study. Genet Epidemiol 19:81-94.
  37. Wilk JB, Premkumar S, Nicolaou M, Myers RH, Maher NE, Harmon MD, Farrer LA, DeStefano AL, Cupples LA, Couropmitree NN (1999): Stratification Techniques to Explore Genotype Environment Interactions. Genet Epidemiol 17(Suppl 1):S761-S766.